该论文题目为《 Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia 》,本研究以 APP/PS1 阿尔茨海默病小鼠为模型,发现游泳运动可促进骨骼肌分泌含 miR-378a-3p 的细胞外囊泡,该囊泡能促进淀粉样蛋白斑块清除,改善小鼠认知障碍,而过表达 miR-378a-3p 的肌管来源囊泡可模拟该效果,为 AD 提供了运动模拟型治疗新策略。
Pushing a CA file into the right spot,详情可参考PDF资料
Analyze engagement metrics,详情可参考新收录的资料
// ManagedBlocker 接口:执行阻塞,详情可参考新收录的资料
Concerns about the wider implications of such a change pulsed through discussions at the World Economic Forum in Davos last month and have contributed to widespread economic anxiety in the US.